The Seagulls will be looking to continue their good form since the restart which saw them record a 2-1 win over Arsenal and a 0-0 draw at Leicester City.
Neal Maupay was the hero against the Gunners, adding to Lewis Dunk’s equaliser with a stoppage time winner to give Graham Potter’s men three vital points.
The French striker had a golden chance against Leicester too, but saw his penalty saved in the 0-0 draw at the King Power Stadium.
Manchester United were 2-1 winners after extra time against Norwich City in the Emirates FA Cup on Saturday after making eight changes to the side that beat Sheffield United 3-0 last Wednesday when Anthony Martial scored a hat-trick.
Odion Ighalo had fired the visitors into a second half lead at Carrow Road, before Todd Cantwell levelled for the home side with 15 minutes remaining.
Timm Klose saw red for the Canaries before the game went to extra time, with captain Harry Maguire poking home with two minutes left to play to send the Red Devils into the last four.
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Graham Potter confirmed that Jose Izquierdo would miss Tuesday’s game when he spoke to the media on Monday, while a decision is to be made on defender Adam Webster. Tariq Lamptey will make the match against United, despite picking up a facial injury against the Foxes.
"Adam Webster has made good progress but we're waiting on him. He'll be touch and go for tomorrow," he said.
"Tariq Lamptey has had stitches, but he's okay for tomorrow."
The Red Devils will be without the injured defensive duo of Axel Tuanzebe and Phil Jones.
Our last fixture…
Albion line-up: Ryan (GK); Lamptey, Dunk, Webster (Duffy 24), Burn; Bissouma (Propper 58), Mooy, Stephens; Mac Allister (March 58), Maupay (Trossard 57), Connolly (Murray 82).
Subs not used: Button (GK); Schelotto, Montoya, Gross.
Their last fixture…
Norwich City 1
Man United 2
Man Utd win AET.
Man United line-up: Romero (GK); Dalot (Williams 63), Bailly (Martial 96), Maguire, Shaw; Mata (Greenwood 63), Lingard (Rashford 63), Fred (Pogba 78), McTominay (Matic 78), Fernandes; Ighalo.
Subs not used: De Gea, Fosu-Mensah, Pereira.
The Manchester United player to watch…
Bruno Fernandes has caught the eye since his January arrival from Sporting Lisbon.
The midfielder scored in three consecutive games in all competitions before the lockdown. He netted in the 3-0 home league win over Watford, before finding the net in the 5-0 victory over Club Brugge in the Europa League four days later.
He then earned Solskjaer’s men a share of the spoils in a 1-1 draw with Everton at Goodison Park the following weekend and was on target in the side’s first game of Project Restart when the Red Devils drew 1-1 at Tottenham.
Referee: Andre Marriner. Assistants: Constantine Hatzidakis, Neil Davies. Fourth official: Stuart Attwell. Replacement official: Ian Cooper. VAR: Andy Madley. Assistant VAR: Andy Garratt.